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UCH-L1 expression of podocytes in diseased glomeruli and in vitro

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Zhang K, Li R, Matniyaz Y, Yu R, Pan J, Liu W, et al

Individual safety findings for one molecule dont necessarily predict class-wide effects, says Finer, safety signals often relate to specific structural features or off-target activities rather than the primary mechanism of action. He thinks oral GLP-1 drugs have the potential for better dose titration, which might help control the current, mainly gastrointestinal, side-effects of the injectable peptides

Since stopping and starting is so common, my colleagues and I thought it was worth investigating whether or not the GLP-1s work as well each time, said Leung